Mannatech Science
Ingredient Information

Ingredient Information

About the ingredients in Mannatech’s products

Mannatech’s products are formulated using high quality natural ingredients. This section contains scientific information about the components of many foods and ingredients in dietary supplements.

OpenVanadium

Vanadium

Vanadium is a trace element found in foods such as mushrooms, shellfish, black pepper, parsley, grains and grain products. The absorption of ingested vanadium is less than 5 percent (1).
     A biological role of vanadium in humans is unclear. Therefore, neither a Reference Daily Intake (RDI) nor a Daily Reference Value (DRV) has been set by the U.S. Food and Drug Administration (FDA).

This ingredient can be found in the following products:
   •  Catalyst™ caplets
   •  GlycoBears® tablets
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

Last updated March, 2009

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OpenVanadium (as vanadium glycinate)

Vanadium (as vanadium glycinate)

Vanadium is a trace element found in foods such as mushrooms, shellfish, black pepper, parsley, grains and grain products. The absorption of ingested vanadium is less than 5 percent (1).
     A biological role of vanadium in humans is unclear. Therefore, neither a Reference Daily Intake (RDI) nor a Daily Reference Value (DRV) has been set by the U.S. Food and Drug Administration (FDA).
     Vanadium glycinate, or vanadyl glycinate, is a form of chelated vanadium, in which a vanadium ion is bound to the amino acid glycine. It is used as a source of the trace mineral vanadium in dietary supplements.

This ingredient can be found in the following products:
   •  GlycoBears® tablets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

Last updated April, 2009

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OpenVanadium (as vanadyl glycinate)

Vanadium (as vanadyl glycinate)

Vanadium is a trace element found in foods such as mushrooms, shellfish, black pepper, parsley, grains and grain products. The absorption of ingested vanadium is less than 5 percent (1).
     A biological role of vanadium in humans is unclear. Therefore, neither a Reference Daily Intake (RDI) nor a Daily Reference Value (DRV) has been set by the U.S. Food and Drug Administration (FDA).
     Vanadyl glycinate, or vanadium glycinate, is a form of chelated vanadium, in which a vanadium ion is bound to the amino acid glycine. It is used as a source of the trace mineral vanadium in dietary supplements.

This ingredient can be found in the following products:
   •  Catalyst™ caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

Last updated April, 2009

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OpenVanadium (from mustard sprout)

Vanadium (from mustard sprout)

Vanadium is a trace element found in foods such as mushrooms, shellfish, black pepper, parsley, grains and grain products. The absorption of ingested vanadium is less than 5 percent (1).
     A biological role of vanadium in humans is unclear. Therefore, neither a Reference Daily Intake (RDI) nor a Daily Reference Value (DRV) has been set by the U.S. Food and Drug Administration (FDA).
     Mustard sprout. The greens and seeds of the Indian, or brown mustard plant, Brassica juncea, have been cultivated in Asia and Europe for thousands of years (2). Growing Indian mustard sprouts in mineral-enriched soil can increase the amount of minerals concentrated in the plant’s tissue. The sprouts can then be used in dietary supplements as sources of essential and trace minerals such as chromium, iron, manganese, selenium and zinc (3).

This ingredient can be found in the following products:
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

2. Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. The Concise Encyclopedia of Foods and Nutrition. Boca Raton, Florida: CRC Press, 1995.

3. Elless M, Blaylock M, Huang J. Plants as a natural source of concentrated mineral nutritional supplements. Food Chem 2000;71:181-8.

Last updated April, 2009

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OpenVanadium glycinate

Vanadium glycinate

Vanadium glycinate, or vanadyl glycinate, is a form of chelated vanadium, in which a vanadium ion is bound to the amino acid glycine. It is used as a source of the trace mineral vanadium in dietary supplements.

This ingredient can be found in the following products:
   •  GlycoBears® tablets
 

References

References

   

Last updated April, 2009

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OpenVanadyl glycinate

Vanadyl glycinate

Vanadyl glycinate, or vanadium glycinate, is a form of chelated vanadium, in which a vanadium ion is bound to the amino acid glycine. It is used as a source of the trace mineral vanadium in dietary supplements.

This ingredient can be found in the following products:
   •  Catalyst™ caplets
 

References

References

   

Last updated April, 2009

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OpenVegetable capsule

Vegetable capsule

Vegetable capsules are all-natural, vegetarian-friendly alternatives to the typical gelatin capsule, made with vegetable cellulose instead of animal-derived gelatin.

This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Ambrotose AO® capsules
 

References

References

   

Last updated March, 2009

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OpenVegetable cellulose

Vegetable cellulose

Vegetable cellulose. Cellulose is a natural compound found in the cell walls of many plants. Powdered cellulose is added to tablets and capsules for a variety of reasons: to dilute the ingredients in tablets or capsules or to help tablets disintegrate following ingestion. Powdered cellulose is not absorbed systemically following oral ingestion and thus has little potential for toxicity. While consumption of large amounts (i.e., 6 g) may have a laxative effect, this is not a concern for individuals consuming the small amounts used as formulation aids in dietary supplements (1).

This ingredient can be found in the following products:
   •  Accelerator 3™ capsules
   •  Ambrotose® Complex capsules
   •  BounceBack® capsules
   •  FiberSlim™ capsules
   •  GI-PRO® capsules
   •  GI-ZYME® capsules
   •  Manna-C™ capsules
   •  Optimal Support Packets
   •  Phyt-Aloe® capsules or powder
 

References

References

1. Handbook of Pharmaceutical Excipients. Gurnee, IL: Pharmaceutical Press, 2006.

Last updated March, 2009

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OpenVegetable juice color

Vegetable juice color

Vegetable juice color is prepared either by expressing the juice from fresh, ripe vegetables, or by the water infusion of dried vegetables. Vegetable juice is approved for use in the coloring of foods by the U.S. Food and Drug Administration (FDA) (21CFR73.260) (1).

This ingredient can be found in the following products:
   •  MannaBears™ supplement
   •  PhytoBurst® nutritional chews
 

References

References

1. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

Last updated March, 2009

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OpenVegetable magnesium stearate

Vegetable magnesium stearate

Magnesium stearate, a salt of stearic acid, is widely used in cosmetics, foods, and capsules as a lubricating agent. In dietary supplements it may contain a mixture of magnesium salts of different fatty acids. 
     Magnesium stearate is approved by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS) (21CFR184.1440) and is generally regarded as being nontoxic following oral administration. Oral consumption of large quantities may produce a laxative effect or cause mucosal irritation (1).

This ingredient can be found in the following products:
   •  Accelerator 3™ capsules
   •  ImmunoSTART® tablets
 

References

References

1. Handbook of Pharmaceutical Excipients. Gurnee, IL: Pharmaceutical Press, 2006.

Last updated March, 2009

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OpenVegetable stearic acid

Vegetable stearic acid

Stearic acid is a naturally occurring fatty acid that is found in animal and vegetable fats. In dietary supplements, it is typically a combination of stearic and palmitic acids. Stearic acid is used as a lubricantin capsules and tablets and is also used widely in cosmetics and food products (1).Stearic acid is approved by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS) (21CFR184.1090)and is generally regarded as a nontoxic and nonirritating material (1).

This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  ImmunoSTART® tablets
   •  Manna-C™ capsules
 

References

References

1. Handbook of Pharmaceutical Excipients. Gurnee, IL: Pharmaceutical Press, 2006.

Last updated March, 2009

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OpenVitamin A

Vitamin A

Vitamin A, also called retinol, is a fat-soluble vitamin that is essential for humans. Adequate intake is important for normal vision and immune function. Dietary vitamin A can be provided as both preformed vitamin A and provitamin A carotenoids that are precursors to vitamin A. Preformed vitamin A is abundant in animal-derived foods like liver, kidney, eggs, and dairy products. Carotenoids, like beta-carotene, are found in darkly colored fruits and vegetables. Preformed vitamin A is efficiently absorbed through the intestines, while carotenoids may either be absorbed through the intestines intact or cleaved to form vitamin A prior to absorption. The proportion of beta-carotene converted to vitamin A decreases as beta-carotene intake increases, limiting the risk of vitamin A toxicity (1).
     Dietary preformed vitamin A and provitamin A carotenoids have vitamin A activity that can be expressed as retinol activity equivalents (RAEs) or international units (IU). In the U.S., 1 RAE is equal to 3.33 IU vitamin A. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 5,000 IUs vitamin A for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.

This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Advanced Ambrotose® powder
   •  AmbroStart® drink mix
   •  Ambrotose® Complex capsules
   •  Catalyst™ caplets
   •  GlycoBears® tablets
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

Last updated March, 2009

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OpenVitamin A (100% as beta-carotene)

Vitamin A (100% as beta-carotene)

Vitamin A, also called retinol, is a fat-soluble vitamin that is essential for humans. Adequate intake is important for normal vision and immune function. Dietary vitamin A can be provided as both preformed vitamin A and provitamin A carotenoids that serve as precursors to vitamin A (1). Preformed vitamin A is abundant in animal-derived foods like liver, kidney, eggs, and dairy products. Carotenoids, like beta-carotene, are found in darkly colored fruits and vegetables.
     Dietary preformed vitamin A and provitamin A carotenoids have vitamin A activity that can be expressed as retinol activity equivalents (RAEs) or international units (IU). In the U.S., 1 RAE is equal to 3.33 IU vitamin A. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 5,000 IUs vitamin A for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Beta-carotene is a member of the plant-produced compounds called carotenoids. Beta-carotene is a potent antioxidant. The ultimate source of all vitamin A is from the carotenes, and beta-carotene has the highest vitamin A activity (2). Beta-carotene is particularly abundant in orange vegetables and fruit, and may be directly added to foods as a vitamin supplement (3).
     Carotenoids may either be absorbed through the intestines intact, or be cleaved to form vitamin A prior to absorption. The proportion of beta-carotene converted to vitamin A decreases as beta-carotene intake increases, limiting the risk of vitamin A toxicity (1). Beta-carotene supplementation in humans is likely safe over long periods of time.

This ingredient can be found in the following products:
   •  AmbroStart® drink mix
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

2. Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. The Concise Encyclopedia of Foods and Nutrition. Boca Raton, Florida: CRC Press, 1995.

3. Food and Drugs. Title 21, U.S. Code of Federal Regulations. 1999. 21CFR. Ref Type: Bill/Resolution

Last updated March, 2009

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OpenVitamin A (as Dunaliella salina isolate [alpha-, beta-carotene, cryptoxanthin, zeaxanthin, lutein])

Vitamin A (as Dunaliella salina isolate [alpha-, beta-carotene, cryptoxanthin, zeaxanthin, lutein])

Vitamin A, also called retinol,is a fat-soluble vitamin that is essential for humans. Adequate intake is important for normal vision and immune function. Dietary vitamin A can be provided as both preformed vitamin A and provitamin A carotenoids that are precursors to vitamin A. Preformed vitamin A is abundant in animal-derived foods like liver, kidney, eggs, and dairy products. Carotenoids, like beta-carotene, are found in darkly colored fruits and vegetables. Preformed vitamin A is efficiently absorbed through the intestines, while carotenoids may either be absorbed through the intestines intact or cleaved to form vitamin A prior to absorption. The proportion of beta-carotene converted to vitamin A decreases as beta-carotene intake increases, limiting the risk of vitamin A toxicity (1).
     Dietary preformed vitamin A and provitamin A carotenoids have vitamin A activity that can be expressed as retinol activity equivalents (RAEs) or international units (IU). In the U.S., 1 RAE is equal to 3.33 IU vitamin A. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 5,000 IUs vitamin A for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Dunaliella salina is a species of single-celled algae that grows in high salt waters. It is known for its antioxidant activity due to the fact that it contains a large amount of carotenoids. The presence of beta-carotene makes the algae appear red in color. Dunaliella salina can be used a source of carotenoids for dietary supplements (2).

This ingredient can be found in the following products:
   •  Catalyst™ caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

2. Oren A. A hundred years of Dunaliella research: 1905-2005. Saline.Systems. 2005;1:2.

Last updated April, 2009

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OpenVitamin A (as mixed caroteniods from Blakeslea trispora fungus)

Vitamin A (as mixed caroteniods from Blakeslea trispora fungus)

Vitamin A, also called retinol, is a fat-soluble vitamin that is essential for humans. Adequate intake is important for normal vision and immune function. Dietary vitamin A can be provided as both preformed vitamin A and provitamin A carotenoids that are precursors to vitamin A. Preformed vitamin A is abundant in animal-derived foods like liver, kidney, eggs, and dairy products. Carotenoids, like beta-carotene, are found in darkly colored fruits and vegetables. Preformed vitamin A is efficiently absorbed through the intestines, while carotenoids may either be absorbed through the intestines intact or cleaved to form vitamin A prior to absorption. The proportion of beta-carotene converted to vitamin A decreases as beta-carotene intake increases, limiting the risk of vitamin A toxicity (1).
     Dietary preformed vitamin A and provitamin A carotenoids have vitamin A activity that can be expressed as retinol activity equivalents (RAEs) or international units (IU). In the U.S., 1 RAE is equal to 3.33 IU vitamin A. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 5,000 IUs vitamin A for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Blakeslea trispora is a fungus that can be used as a source of carotenoids, such as beta-carotene, gamma-carotene and lycopene, for dietary supplements (2), (3).

This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Advanced Ambrotose® powder
   •  Ambrotose® Complex capsules
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

2. Olempska-Beer Z. U.S. Food and Drug Administration. Lycopene from Blakeslea trispora Chemical and Technical Assessment. 2006. College Park, Maryland.

3. Jeong J, Lee I, Kim S, Park Y. Stimulation of beta-carotene synthesis by hydrogen peroxide in Blakeslea trispora. Biotechnology Letters 1999;21:683–6.

Last updated November, 2009

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OpenVitamin A (as mixed carotenoids)

Vitamin A (as mixed carotenoids)

Vitamin A, also called retinol, is a fat-soluble vitamin that is essential for humans. Adequate intake is important for normal vision and immune function. Dietary vitamin A can be provided as both preformed vitamin A and provitamin A carotenoids that are precursors to vitamin A. Preformed vitamin A is abundant in animal-derived foods like liver, kidney, eggs, and dairy products. Carotenoids, like beta-carotene, are found in darkly colored fruits and vegetables. Preformed vitamin A is efficiently absorbed through the intestines, while carotenoids may either be absorbed through the intestines intact or cleaved to form vitamin A prior to absorption. The proportion of beta-carotene converted to vitamin A decreases as beta-carotene intake increases, limiting the risk of vitamin A toxicity (1).
     Dietary preformed vitamin A and provitamin A carotenoids have vitamin A activity that can be expressed as retinol activity equivalents (RAEs) or international units (IU). In the U.S., 1 RAE is equal to 3.33 IU vitamin A. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 5,000 IUs vitamin A for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.

This ingredient can be found in the following products:
   •  Optimal Support Packets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

Last updated March, 2009

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OpenVitamin A (as retinyl palmitate, beta-carotene and Dunaliella salina extract [alpha-carotene, cryptoxanthin, zeaxanthin, lutein])

Vitamin A (as retinyl palmitate, beta-carotene and Dunaliella salina extract [alpha-carotene, cryptoxanthin, zeaxanthin, lutein])

Vitamin A, also called retinol,is a fat-soluble vitamin that is essential for humans. Adequate intake is important for normal vision and immune function. Dietary vitamin A can be provided as both preformed vitamin A and provitamin A carotenoids that serve as precursors to vitamin A (1). Preformed vitamin A is abundant in animal-derived foods like liver, kidney, eggs, and dairy products. Carotenoids, like beta-carotene, are found in darkly colored fruits and vegetables.
     Dietary preformed vitamin A and provitamin A carotenoids have vitamin A activity that can be expressed as retinol activity equivalents (RAEs) or international units (IU). In the U.S., 1 RAE is equal to 3.33 IU vitamin A. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 5,000 IUs vitamin A for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Retinyl palmitate, or vitamin A palmitate, is an ester of retinol and palmitic acid. It is commonly used as a source of vitamin A in dietary supplements and fortified foods, such as milk. Retinyl palmitate is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use as a nutrient supplement in foods (21CFR184.1930) (2).
     Beta-carotene is a member of the plant-produced compounds called carotenoids. Beta-carotene is a potent antioxidant. The ultimate source of all vitamin A is from the carotenes, and beta-carotene has the highest vitamin A activity (3). Beta-carotene is particularly abundant in orange vegetables and fruit, and may be directly added to foods as a vitamin supplement (4).
     Dunaliella salina is a species of single-celled algae that grows in high salt waters. It is known for its antioxidant activity due to the fact that it contains a large amount of carotenoids. The presence of beta-carotene makes the algae appear red in color. Dunaliella salina can be used a source of carotenoids for dietary supplements (5).

This ingredient can be found in the following products:
   •  GlycoBears® tablets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, D.C.: National Academy Press, 2002.

2. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

3. Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. The Concise Encyclopedia of Foods and Nutrition. Boca Raton, Florida: CRC Press, 1995.

4. Food and Drugs. Title 21, U.S. Code of Federal Regulations. 1999. 21CFR.
Ref Type: Bill/Resolution

5. Oren A. A hundred years of Dunaliella research: 1905-2005. Saline.Systems. 2005;1:2.

Last updated April, 2009

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OpenVitamin B12

Vitamin B12

Vitamin B12 is an essential water-soluble vitamin that is commonly found in a variety of animal foods such as fish, shellfish, meat and dairy products. Synthetic vitamin B12 is frequently used in combination with other B vitamins in vitamin B complex formulations and added to supplements and fortified foods such as cereals. An adequate supply of vitamin B12 is essential to maintain healthy nerve cell and red blood cell function, as well as for folate utilization. The average fractional absorption of vitamin B12 from food by healthy individuals is approximately 50 percent, while synthetic vitamin B12 has increased bioavailability (1).
     No adverse effects have been associated with vitamin B12 intake from food or supplements in healthy individuals (1). The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 6 μg vitamin B12 for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.

This ingredient can be found in the following products:
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  GlycoBears® tablets
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press, 2000.

Last updated March, 2009

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OpenVitamin B12 (as cyanocobalamin)

Vitamin B12 (as cyanocobalamin)

Vitamin B12 is an essential water-soluble vitamin that is commonly found in a variety of animal foods such as fish, shellfish, meat and dairy products. Synthetic vitamin B12 is frequently used in combination with other B vitamins in vitamin B complex formulations and added to supplements and fortified foods such as cereals. An adequate supply of vitamin B12 is essential to maintain healthy nerve cell and red blood cell function, as well as for folate utilization. The average fractional absorption of vitamin B12 from food by healthy individuals is approximately 50 percent, while synthetic vitamin B12 has increased bioavailability (1).
     No adverse effects have been associated with vitamin B12 intake from food or supplements in healthy individuals (1). The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 6 μg vitamin B12 for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Cyanocobalamin is the principal form of vitamin B12 for commercial use in fortified foods and dietary supplements. Once absorbed through the intestine, cyanocobalamin is converted to the active forms of vitamin B12 in the body.

This ingredient can be found in the following products:
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  GlycoBears® tablets
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press, 2000.

Last updated March, 2009

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OpenVitamin B6

Vitamin B6

Vitamin B6, or pyridoxine, is a water-soluble vitamin that functions as a coenzyme in the metabolism of amino acids and the release of glucose from glycogen (1). Major sources of vitamin B6 include fortified, ready-to-eat cereals; mixed foods (including sandwiches) with meat, fish or poultry as the main ingredient; white potatoes and other starchy vegetables; and non-citrus fruits. Vitamin B6 is frequently used in combination with other B vitamins in vitamin B complex formulations.
     Vitamin B6 is generally considered safe in adults and children when used appropriately at recommended doses. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 2.0 mg vitamin B6 for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.

This ingredient can be found in the following products:
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  GlycoBears® tablets
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press, 2000.

Last updated March, 2009

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OpenVitamin B6 (as pyridoxine hydrochloride and pyridoxal 5-phosphate)

Vitamin B6 (as pyridoxine hydrochloride and pyridoxal 5-phosphate)

Vitamin B6, or pyridoxine, is a water-soluble vitamin that functions as a coenzyme in the metabolism of amino acids and the release of glucose from glycogen (1). Major sources of vitamin B6 include fortified, ready-to-eat cereals; mixed foods (including sandwiches) with meat, fish or poultry as the main ingredient; white potatoes and other starchy vegetables; and non-citrus fruits. Vitamin B6 is frequently used in combination with other B vitamins in vitamin B complex formulations.
     Vitamin B6 is generally considered safe in adults and children when used appropriately at recommended doses. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 2.0 mg vitamin B6 for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Pyridoxine hydrochloride is a form of vitamin B6 used in fortified foods and nutritional supplements. Pyridoxine hydrochloride is considered generally recognized as safe (GRAS) for use as a direct food ingredient by the U.S. Food and Drug Administration (FDA) (21CFR184.1676).
     Pyridoxal 5’-phosphate (P5P) is the active coenzyme form of vitamin B6, involved in amino acid metabolism and numerous other enzymatic reactions in the human body. Pyridoxal 5’-phosphate is considered a particularly useful nutrient supplement, because all other forms of vitamin B6 must be converted to P5P in the liver before they are considered active. The P5P form of vitamin B6 is typically found in foods of animal origin, such as meats, dairy products and eggs. No adverse effects have been associated with high intake of vitamin B6 from food sources (1).

This ingredient can be found in the following products:
   •  CardioBALANCE® capsules
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press, 2000.

Last updated March, 2009

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OpenVitamin B6 (as pyridoxine hydrochloride)

Vitamin B6 (as pyridoxine hydrochloride)

Vitamin B6, or pyridoxine, is a water-soluble vitamin that functions as a coenzyme in the metabolism of amino acids and the release of glucose from glycogen (1). Major sources of vitamin B6 include fortified, ready-to-eat cereals; mixed foods (including sandwiches) with meat, fish or poultry as the main ingredient; white potatoes and other starchy vegetables; and non-citrus fruits. Vitamin B6 is frequently used in combination with other B vitamins in vitamin B complex formulations.
     Vitamin B6 is generally considered safe in adults and children when used appropriately at recommended doses. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 2.0 mg vitamin B6 for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Pyridoxine hydrochloride is a form of vitamin B6 used in fortified foods and nutritional supplements. Pyridoxine hydrochloride is considered generally recognized as safe (GRAS) for use as a direct food ingredient by the U.S. Food and Drug Administration (FDA) (21CFR184.1676).

This ingredient can be found in the following products:
   •  GlycoBears® tablets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press, 2000.

Last updated March, 2009

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OpenVitamin B6 (as pyridoxine hydrochloride, pyridoxine 5-phosphate)

Vitamin B6 (as pyridoxine hydrochloride, pyridoxine 5-phosphate)

Vitamin B6, or pyridoxine, is a water-soluble vitamin that functions as a coenzyme in the metabolism of amino acids and the release of glucose from glycogen (1). Major sources of vitamin B6 include fortified, ready-to-eat cereals; mixed foods (including sandwiches) with meat, fish or poultry as the main ingredient; white potatoes and other starchy vegetables; and non-citrus fruits. Vitamin B6 is frequently used in combination with other B vitamins in vitamin B complex formulations.
     Vitamin B6 is generally considered safe in adults and children when used appropriately at recommended doses. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 2.0 mg vitamin B6 for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Pyridoxine hydrochloride is a form of vitamin B6 used in fortified foods and nutritional supplements. Pyridoxine hydrochloride is considered generally recognized as safe (GRAS) for use as a direct food ingredient by the U.S. Food and Drug Administration (FDA) (21CFR184.1676).
     Pyridoxine 5-phosphate (PNP) is the phosphorylated form of pyridoxine, or vitamin B6. In the body, it acts as an intermediate in the conversion of pyridoxine to the active form of vitamin B6, pyridoxal 5-phosphate. The PNP form of vitamin B6 can be found in plant-derived foods. No adverse effects have been associated with high intake of vitamin B6 from food sources (1).

This ingredient can be found in the following products:
   •  Catalyst™ caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press, 2000.

Last updated April, 2009

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OpenVitamin B6 (from baker’s yeast)

Vitamin B6 (from baker’s yeast)

Vitamin B6, or pyridoxine, is a water-soluble vitamin that functions as a coenzyme in the metabolism of amino acids and the release of glucose from glycogen (1). Major sources of vitamin B6 include fortified, ready-to-eat cereals; mixed foods (including sandwiches) with meat, fish or poultry as the main ingredient; white potatoes and other starchy vegetables; and non-citrus fruits. Vitamin B6 is frequently used in combination with other B vitamins in vitamin B complex formulations.
     Vitamin B6 is generally considered safe in adults and children when used appropriately at recommended doses. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 2.0 mg vitamin B6 for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Baker’s yeast, Saccharomyces cerevisiae, also known as brewer’s yeast, is a yeast often used for baking or brewing. It is an excellent source of the essential B vitamins, including folic acid, niacin, biotin, pantothenic acid, riboflavin, thiamin and vitamin B6 (2).

This ingredient can be found in the following products:
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press, 2000.

2. Natural Medicines. Comprehensive Database. Therapeutic Research Faculty, 2003.

Last updated April, 2009

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OpenVitamin C

Vitamin C

Vitamin C, also called ascorbic acid, is an essential water-soluble vitamin found mainly in fruits and vegetables, particularly in citrus fruits such as oranges. Vitamin C functions as a reducing agent and thereby demonstrates potent antioxidant activity. Vitamin C deficiency can lead to the disease scurvy, which involves the deterioration of elastic tissue, demonstrating the important role of ascorbic acid in the synthesis of connective tissues such as collagen in bones (1). Dietary vitamin C is efficiently absorbed through the intestine.
     Vitamin C is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) (21CFR182.8013). The U.S. FDA has established a Reference Daily Intake (RDI) of 60 mgs vitamin C for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.

This ingredient can be found in the following products:
   •  Ambrotose AO® capsules
   •  BounceBack® capsules
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  GlycoBears® tablets
   •  Manna-C™ capsules
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

Last updated March, 2009

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OpenVitamin C (as ascorbic acid)

Vitamin C (as ascorbic acid)

Vitamin C, also called ascorbic acid, is an essential water-soluble vitamin found mainly in fruits and vegetables, particularly in citrus fruits such as oranges. Vitamin C functions as a reducing agent and thereby demonstrates potent antioxidant activity. Vitamin C deficiency can lead to the disease scurvy, which involves the deterioration of elastic tissue, demonstrating the important role of ascorbic acid in the synthesis of connective tissues such as collagen in bones (1). Dietary vitamin C is efficiently absorbed through the intestine.
     Vitamin C is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) (21CFR182.8013). The U.S. FDA has established a Reference Daily Intake (RDI) of 60 mgs vitamin C for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.

This ingredient can be found in the following products:
   •  Ambrotose AO® capsules
   •  Catalyst™ caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

Last updated March, 2009

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OpenVitamin C (as ascorbic acid, acerola extract [fruit], camu-camu extract [fruit])

Vitamin C (as ascorbic acid, acerola extract [fruit], camu-camu extract [fruit])

Vitamin C, also called ascorbic acid, is an essential water-soluble vitamin found mainly in fruits and vegetables, particularly in citrus fruits such as oranges. Vitamin C functions as a reducing agent and thereby demonstrates potent antioxidant activity. Vitamin C deficiency can lead to the disease scurvy, which involves the deterioration of elastic tissue, demonstrating the important role of ascorbic acid in the synthesis of connective tissues such as collagen in bones (1). Dietary vitamin C is efficiently absorbed through the intestine.
     Vitamin C is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) (21CFR182.8013). The U.S. FDA has established a Reference Daily Intake (RDI) of 60 mgs vitamin C for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Acerola extract is obtained from the fruit of the small tree, Malpighia glabra or Malpighia punicifolia. Acerola is grown in tropical regions of the Americas. The fruit is known for being one of the richest natural sources of vitamin C and also contains vitamin A, thiamin, riboflavin, niacin and polyphenols, such as anthocyanins. Acerola fruit extract acts as an antioxidant, likely due to the presence of some of these nutrients (2). Most acerola fruit is processed into fruit products, such as jams, jellies and juices, or added to dietary supplements as a source of vitamin C (3).
     Camu-camu extract is obtained from the fruit of the small tree, Myrciaria paraensis or Myrciaria dubia. Camu-camu grows in areas of the Amazon rainforest, and the fruit is eaten fresh or made into jam, jelly or wine (3). Camu-camu fruit is one of the richest natural sources of vitamin C, and it contains polyphenolic compounds called anthocyanins (4). These nutrients likely contribute to the fruit’s antioxidant activities (5).

This ingredient can be found in the following products:
   •  CardioBALANCE® capsules
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. Natural Standard Database. www.naturalstandard.com. 2009.

3. Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. The Concise Encyclopedia of Foods and Nutrition. Boca Raton, Florida: CRC Press, 1995.

4. Zanatta CF, Cuevas E, Bobbio FO, Winterhalter P, Mercadante AZ. Determination of anthocyanins from camu-camu (Myrciaria dubia) by HPLC-PDA, HPLC-MS, and NMR. J Agric Food Chem 2005;53:9531-5.

5. Inoue T, Komoda H, Uchida T, Node K. Tropical fruit camu-camu (Myrciaria dubia) has anti-oxidative and anti-inflammatory properties. J Cardiol. 2008;52:127-32.

Last updated March, 2009

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OpenVitamin C (as ascorbic acid, sodium ascorbate and acerola extract [fruit])

Vitamin C (as ascorbic acid, sodium ascorbate and acerola extract [fruit])

Vitamin C, also called ascorbic acid, is an essential water-soluble vitamin found mainly in fruits and vegetables, particularly in citrus fruits such as oranges. Vitamin C functions as a reducing agent and thereby demonstrates potent antioxidant activity. Vitamin C deficiency can lead to the disease scurvy, which involves the deterioration of elastic tissue, demonstrating the important role of ascorbic acid in the synthesis of connective tissues such as collagen in bones (1). Dietary vitamin C is efficiently absorbed through the intestine.
     Vitamin C is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) (21CFR182.8013). The U.S. FDA has established a Reference Daily Intake (RDI) of 60 mgs vitamin C for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Sodium ascorbate is the sodium salt of ascorbic acid. It is used in dietary supplements as a source of ascorbic acid, or vitamin C.
     Acerola extract is obtained from the fruit of the small tree, Malpighia glabra or Malpighia punicifolia. Acerola is grown in tropical regions of the Americas. The fruit is known for being one of the richest natural sources of vitamin C and also contains vitamin A, thiamin, riboflavin, niacin and polyphenols, such as anthocyanins. Acerola fruit extract acts as an antioxidant, likely due to the presence of some of these nutrients (2). Most acerola fruit is processed into fruit products, such as jams, jellies and juices, or added to dietary supplements as a source of vitamin C (3).

This ingredient can be found in the following products:
   •  GlycoBears® tablets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. Natural Standard Database. www.naturalstandard.com. 2009.

3. Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. The Concise Encyclopedia of Foods and Nutrition. Boca Raton, Florida: CRC Press, 1995.

Last updated April, 2009

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OpenVitamin C (as ascorbyl palmitate)

Vitamin C (as ascorbyl palmitate)

Vitamin C, also called ascorbic acid, is an essential water-soluble vitamin found mainly in fruits and vegetables, particularly in citrus fruits such as oranges. Vitamin C functions as a reducing agent and thereby demonstrates potent antioxidant activity. Vitamin C deficiency can lead to the disease scurvy, which involves the deterioration of elastic tissue, demonstrating the important role of ascorbic acid in the synthesis of connective tissues such as collagen in bones (1). Dietary vitamin C is efficiently absorbed through the intestine.
     The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 60 mgs vitamin C for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Ascorbyl palmitate is an ester of vitamin C and palmitic acid. It functions as an antioxidant in oral preparations. Ascorbyl palmitate is approved by the U.S. FDA as generally recognized as safe (GRAS) (21CFR182.3149).

This ingredient can be found in the following products:
   •  BounceBack® capsules
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

Last updated March, 2009

Print This Ingredient
OpenVitamin C (from acerola fruit extract and ascorbic acid)

Vitamin C (from acerola fruit extract and ascorbic acid)

Vitamin C, also called ascorbic acid, is an essential water-soluble vitamin found mainly in fruits and vegetables, particularly in citrus fruits such as oranges. Vitamin C functions as a reducing agent and thereby demonstrates potent antioxidant activity. Vitamin C deficiency can lead to the disease scurvy, which involves the deterioration of elastic tissue, demonstrating the important role of ascorbic acid in the synthesis of connective tissues such as collagen in bones (1). Dietary vitamin C is efficiently absorbed through the intestine.
      Vitamin C is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) (21CFR182.8013). The U.S. FDA has established a Reference Daily Intake (RDI) of 60 mgs vitamin C for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
      Acerola extract is obtained from the fruit of the small tree, Malpighia glabra or Malpighia punicifolia. Acerola is grown in tropical regions of the Americas. The fruit is known for being one of the richest natural sources of vitamin C and also contains vitamin A, thiamin, riboflavin, niacin and polyphenols, such as anthocyanins. Acerola fruit extract acts as an antioxidant, likely due to the presence of some of these nutrients (2). Most acerola fruit is processed into fruit products, such as jams, jellies and juices, or added to dietary supplements as a source of vitamin C (3).

This ingredient can be found in the following products:
   •  Optimal Support Packets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. Natural Standard Database. www.naturalstandard.com. 2009.

3. Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. The Concise Encyclopedia of Foods and Nutrition. Boca Raton, Florida: CRC Press, 1995.

Last updated March, 2009

Print This Ingredient
OpenVitamin C (from acerola fruit extract)

Vitamin C (from acerola fruit extract)

Vitamin C, also called ascorbic acid, is an essential water-soluble vitamin found mainly in fruits and vegetables, particularly in citrus fruits such as oranges. Vitamin C functions as a reducing agent and thereby demonstrates potent antioxidant activity. Vitamin C deficiency can lead to the disease scurvy, which involves the deterioration of elastic tissue, demonstrating the important role of ascorbic acid in the synthesis of connective tissues such as collagen in bones (1). Dietary vitamin C is efficiently absorbed through the intestine.
     Vitamin C is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) (21CFR182.8013). The U.S. FDA has established a Reference Daily Intake (RDI) of 60 mgs vitamin C for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Acerola extract is obtained from the fruit of the small tree, Malpighia glabra or Malpighia punicifolia. Acerola is grown in tropical regions of the Americas. The fruit is known for being one of the richest natural sources of vitamin C and also contains vitamin A, thiamin, riboflavin, niacin and polyphenols, such as anthocyanins. Acerola fruit extract acts as an antioxidant, likely due to the presence of some of these nutrients (2). Most acerola fruit is processed into fruit products, such as jams, jellies and juices, or added to dietary supplements as a source of vitamin C (3).

This ingredient can be found in the following products:
   •  Manna-C™ capsules
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. Natural Standard Database. www.naturalstandard.com. 2009.

3. Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. The Concise Encyclopedia of Foods and Nutrition. Boca Raton, Florida: CRC Press, 1995.

Last updated March, 2009

Print This Ingredient
OpenVitamin D

Vitamin D

Vitamin D is a fat-soluble vitamin that exists in two physiologically relevant forms, ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Ergocalciferol is synthesized by plants, while cholecalciferol is synthesized by humans in the skin when it is exposed to ultraviolet-B (UVB) rays from sunlight. Some foods may also be fortified with vitamin D, such as milk and breakfast cereals. The main function of vitamin D is to regulate serum calcium and phosphorus concentrations within the normal range by enhancing the efficiency of the small intestine to absorb these minerals. By influencing the absorption of calcium, vitamin D helps to form and maintain strong bones. Approximately 80% of ingested vitamin D is absorbed, principally by passive diffusion, in the small intestine (1).
     Vitamin D is generally well tolerated at recommended doses. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 400 international units (IUs) vitamin D for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.

This ingredient can be found in the following products:
   •  Catalyst™ caplets
   •  GlycoBears® tablets
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, D.C.: National Academy Press, 1997.

Last updated March, 2009

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OpenVitamin D (as cholecalciferol)

Vitamin D (as cholecalciferol)

Vitamin D is a fat-soluble vitamin that exists in two physiologically relevant forms, ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Ergocalciferol is synthesized by plants, while cholecalciferol is synthesized by humans in the skin when it is exposed to ultraviolet-B (UVB) rays from sunlight. Some foods may also be fortified with vitamin D, such as milk and breakfast cereals. The main function of vitamin D is to regulate serum calcium and phosphorus concentrations within the normal range by enhancing the efficiency of the small intestine to absorb these minerals. By influencing the absorption of calcium, vitamin D helps to form and maintain strong bones. Approximately 80% of ingested vitamin D is absorbed, principally by passive diffusion, in the small intestine (1).
     Vitamin D is generally well tolerated at recommended doses. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 400 international units (IUs) vitamin D for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Cholecalciferol is a form of vitamin D that is commonly used in dietary supplements. For individuals who are insufficiently exposed to sunlight, vitamin D must be provided through the diet (2).

This ingredient can be found in the following products:
   •  Catalyst™ caplets
   •  GlycoBears® tablets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, D.C.: National Academy Press, 1997.

2. PDR for Nutritional Supplements. Montvale, NJ: Physicians' Desk Reference, Inc, 2008.

Last updated April, 2009

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OpenVitamin D (as plant source ergocalciferol)

Vitamin D (as plant source ergocalciferol)

Vitamin D is a fat-soluble vitamin that exists in two physiologically relevant forms, ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Ergocalciferol is synthesized by plants, while cholecalciferol is synthesized by humans in the skin when it is exposed to ultraviolet-B (UVB) rays from sunlight. Some foods may also be fortified with vitamin D, such as milk and breakfast cereals. The main function of vitamin D is to regulate serum calcium and phosphorus concentrations within the normal range by enhancing the efficiency of the small intestine to absorb these minerals. By influencing the absorption of calcium, vitamin D helps to form and maintain strong bones. Approximately 80% of ingested vitamin D is absorbed, principally by passive diffusion, in the small intestine (1).
     Vitamin D is generally well tolerated at recommended doses. The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 400 international units (IUs) vitamin D for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.

This ingredient can be found in the following products:
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, D.C.: National Academy Press, 1997.

Last updated March, 2009

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OpenVitamin E

Vitamin E

Vitamin E is a fat-soluble vitamin with antioxidant properties. Natural vitamin E exists in eight different forms: alpha, beta, gamma, and delta tocopherol; and alpha, beta, gamma, and delta tocotrienol. Alpha-tocopherol is the most active form in humans. In foods, vitamin E exists primarily as mixed tocopherols. Foods that contain vitamin E include: eggs, fortified cereals, fruit, green leafy vegetables, meat, nuts/nut oils, poultry, vegetable oils and whole grains. Vitamin E supplements are available in natural or synthetic forms. While the precise rate of vitamin E absorption is not known with certainty, it is believed to be variable and low. Reported rates of absorption of vitamin E following intake with food have varied from as high as 51%-86% to as low as 21%-29% (1). All forms of vitamin E, including all of the tocopherol and tocotrienol homologues, are absorbed through the intestine in a similar manner.
     The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 30 international units (IUs) vitamin E for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.

This ingredient can be found in the following products:
   •  Ambrotose AO® capsules
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  GlycoBears® tablets
   •  Optimal Support Packets
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

Last updated March, 2009

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OpenVitamin E (as d-alpha-tocopherol succinate and mixed d-alpha-, d-beta-, d-delta-, and d-gamma-tocopherols)

Vitamin E (as d-alpha-tocopherol succinate and mixed d-alpha-, d-beta-, d-delta-, and d-gamma-tocopherols)

Vitamin E is a fat-soluble vitamin with antioxidant properties. Natural vitamin E exists in eight different forms: alpha, beta, gamma, and delta tocopherol; and alpha, beta, gamma, and delta tocotrienol. Alpha-tocopherol is the most active form in humans. In foods, vitamin E exists primarily as mixed tocopherols. Foods that contain vitamin E include: eggs, fortified cereals, fruit, green leafy vegetables, meat, nuts/nut oils, poultry, vegetable oils and whole grains. Vitamin E supplements are available in natural or synthetic forms. While the precise rate of vitamin E absorption is not known with certainty, it is believed to be variable and low. Reported rates of absorption of vitamin E following intake with food have varied from as high as 51%-86% to as low as 21%-29% (1). All forms of vitamin E, including all of the tocopherol and tocotrienol homologues, are absorbed through the intestine in a similar manner.
     The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 30 international units (IUs) vitamin E for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     D-alpha-tocopherol succinate (also called d-alpha tocopheryl succinate or d-alpha tocopherol acid succinate) is an organic compound derived from vegetable oils that acts as a source of vitamin E. Most ingested d-alpha tocopherol succinate is converted to alpha-tocopherol in the intestine before being absorbed (2). Alpha-tocopherol, like other forms of vitamin E, demonstrates antioxidant activity (3). Alpha tocopherol acid succinate is approved for use as a food additive by the U.S. Food and Drug Administration (FDA) (4).
     Tocopherols, along with tocotrienols, are organic compounds collectively known as vitamin E. Natural tocopherols exist as a mixture of d-alpha-, d-beta-, d-gamma- and d-delta-isoforms, each having antioxidant activities (5). Tocopherols are present in many foods, such as vegetable oils, nuts and grains. They are considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods (21CFR182.3890) (4).

This ingredient can be found in the following products:
   •  GlycoBears® tablets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. PDR for Nutritional Supplements. Montvale, NJ: Physicians' Desk Reference, Inc, 2008.

3. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.

4. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

5. Yoshida Y, Saito Y, Jones LS, Shigeri Y. Chemical reactivities and physical effects in comparison between tocopherols and tocotrienols: physiological significance and prospects as antioxidants. J Biosci Bioeng. 2007;104:439-45.

Last updated April, 2009

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OpenVitamin E (as d-alpha-tocopheryl acetate, mixed d-alpha-, d-beta-, d-delta-, and d-gamma-tocopherols and mixed tocotrienols)

Vitamin E (as d-alpha-tocopheryl acetate, mixed d-alpha-, d-beta-, d-delta-, and d-gamma-tocopherols and mixed tocotrienols)

Vitamin E is a fat-soluble vitamin with antioxidant properties. Natural vitamin E exists in eight different forms: alpha, beta, gamma, and delta tocopherol; and alpha, beta, gamma, and delta tocotrienol. Alpha-tocopherol is the most active form in humans. In foods, vitamin E exists primarily as mixed tocopherols. Foods that contain vitamin E include: eggs, fortified cereals, fruit, green leafy vegetables, meat, nuts/nut oils, poultry, vegetable oils and whole grains. Vitamin E supplements are available in natural or synthetic forms.While the precise rate of vitamin E absorption is not known with certainty, it is believed to be variable and low. Reported rates of absorption of vitamin E following intake with food have varied from as high as 51%-86% to as low as 21%-29% (1). All forms of vitamin E, including all of the tocopherol and tocotrienol homologues, are absorbed through the intestine in a similar manner.
     The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 30 international units (IUs) vitamin E for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     D-alpha-tocopheryl acetate, or D-alpha tocopherol acetate,is an organic compound derived from vegetable oils that acts as a source of vitamin E. The natural form, d-alpha-tocopheryl acetate, is more bioavailable than the synthetic form, dl-alpha-tocopheryl acetate. Alpha-tocopheryl acetate is converted to alpha-tocopherol in the intestine before being absorbed (2). Alpha-tocopherol, like other forms of vitamin E, demonstrates antioxidant activity (3). Alpha-tocopherol acetate is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods (4).
     Tocopherols and tocotrienols are organic compounds collectively known as vitamin E. They naturally exist as a mixture of d-alpha-, d-beta-, d-gamma- and d-delta-isoforms, each having antioxidant activities (5). Tocopherols are present in many foods, such as vegetable oils, nuts and grains. They are considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods (21CFR182.3890) (4). Tocotrienols are present in foods such as cereal grains and cooking oils (i.e. palm, safflower, peanut and olive). Although tocotrienols are not as well studied compared to other forms of vitamin E, such as alpha-tocopherol, the safety of consumption of all forms of vitamin E is considered comparable.

This ingredient can be found in the following products:
   •  CardioBALANCE® capsules
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. Acuff RV, Thedford SS, Hidiroglou NN, Papas AM, Odom TA, Jr. Relative bioavailability of RRR- and all-rac-alpha-tocopheryl acetate in humans: studies using deuterated compounds. Am J Clin Nutr 1994;60:397-402.

3. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.

4. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

5. Yoshida Y, Saito Y, Jones LS, Shigeri Y. Chemical reactivities and physical effects in comparison between tocopherols and tocotrienols: physiological significance and prospects as antioxidants. J Biosci Bioeng. 2007;104:439-45.

Last updated April, 2009

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OpenVitamin E (as d-alpha-tocopheryl succinate, mixed d-alpha-, d-beta-, d-delta-, d-gamma-tocopherols, and tocotrienols)

Vitamin E (as d-alpha-tocopheryl succinate, mixed d-alpha-, d-beta-, d-delta-, d-gamma-tocopherols, and tocotrienols)

Vitamin E is a fat-soluble vitamin with antioxidant properties. Natural vitamin E exists in eight different forms: alpha, beta, gamma, and delta tocopherol; and alpha, beta, gamma, and delta tocotrienol. Alpha-tocopherol is the most active form in humans. In foods, vitamin E exists primarily as mixed tocopherols. Foods that contain vitamin E include: eggs, fortified cereals, fruit, green leafy vegetables, meat, nuts/nut oils, poultry, vegetable oils and whole grains. Vitamin E supplements are available in natural or synthetic forms. While the precise rate of vitamin E absorption is not known with certainty, it is believed to be variable and low. Reported rates of absorption of vitamin E following intake with food have varied from as high as 51%-86% to as low as 21%-29% (1). All forms of vitamin E, including all of the tocopherol and tocotrienol homologues, are absorbed through the intestine in a similar manner.
     The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 30 international units (IUs) vitamin E for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     D-alpha-tocopheryl succinate (also called d-alpha tocopherol succinate or d-alpha tocopherol acid succinate) is an organic compound derived from vegetable oils that acts as a source of vitamin E. Most ingested d-alpha tocopherol succinate is converted to alpha-tocopherol in the intestine before being absorbed (2). Alpha-tocopherol, like other forms of vitamin E, demonstrates antioxidant activity (3). Alpha tocopherol acid succinate is approved for use as a food additive by the U.S. Food and Drug Administration (FDA) (4).
     Tocopherols and tocotrienols are organic compounds collectively known as vitamin E. They naturally exist as a mixture of d-alpha-, d-beta-, d-gamma- and d-delta-isoforms, each having antioxidant activities (5). Tocopherols are present in many foods, such as vegetable oils, nuts and grains. They are considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods (21CFR182.3890) (4). Tocotrienols are present in foods such as cereal grains and cooking oils (i.e. palm, safflower, peanut and olive). Although tocotrienols are not as well studied compared to other forms of vitamin E, such as alpha-tocopherol, the safety of consumption of all forms of vitamin E is considered comparable.

This ingredient can be found in the following products:
   •  Catalyst™ caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. PDR for Nutritional Supplements. Montvale, NJ: Physicians' Desk Reference, Inc, 2008.

3. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.

4. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

5. Yoshida Y, Saito Y, Jones LS, Shigeri Y. Chemical reactivities and physical effects in comparison between tocopherols and tocotrienols: physiological significance and prospects as antioxidants. J Biosci Bioeng. 2007;104:439-45.

Last updated April, 2009

Print This Ingredient
OpenVitamin E (as mixed d-alpha-, d-beta-, d-delta-, and d-gamma-tocopherols)

Vitamin E (as mixed d-alpha-, d-beta-, d-delta-, and d-gamma-tocopherols)

Vitamin E is a fat-soluble vitamin with antioxidant properties. Natural vitamin E exists in eight different forms: alpha, beta, gamma, and delta tocopherol; and alpha, beta, gamma, and delta tocotrienol. Alpha-tocopherol is the most active form in humans. In foods, vitamin E exists primarily as mixed tocopherols. Foods that contain vitamin E include: eggs, fortified cereals, fruit, green leafy vegetables, meat, nuts/nut oils, poultry, vegetable oils and whole grains. Vitamin E supplements are available in natural or synthetic forms. While the precise rate of vitamin E absorption is not known with certainty, it is believed to be variable and low. Reported rates of absorption of vitamin E following intake with food have varied from as high as 51%-86% to as low as 21%-29% (1). All forms of vitamin E, including all of the tocopherol and tocotrienol homologues, are absorbed through the intestine in a similar manner.
     The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 30 international units (IUs) vitamin E for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Tocopherols, along with tocotrienols, are organic compounds collectively known as vitamin E. Natural tocopherols exist as a mixture of d-alpha-, d-beta-, d-gamma- and d-delta-isoforms, each having antioxidant activities (2). Tocopherols are present in many foods, such as vegetable oils, nuts and grains. They are considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods (21CFR182.3890) (3).

This ingredient can be found in the following products:
   •  Ambrotose AO® capsules
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. Yoshida Y, Saito Y, Jones LS, Shigeri Y. Chemical reactivities and physical effects in comparison between tocopherols and tocotrienols: physiological significance and prospects as antioxidants. J Biosci Bioeng. 2007;104:439-45.
 
3. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

 

Last updated March, 2009

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OpenVitamin E (as mixed tocopherols from vegetable oil extract (soy, corn, safflower))

Vitamin E (as mixed tocopherols from vegetable oil extract (soy, corn, safflower))

Vitamin E is a fat-soluble vitamin with antioxidant properties. Natural vitamin E exists in eight different forms: alpha, beta, gamma, and delta tocopherol; and alpha, beta, gamma, and delta tocotrienol. Alpha-tocopherol is the most active form in humans. In foods, vitamin E exists primarily as mixed tocopherols. Foods that contain vitamin E include: eggs, fortified cereals, fruit, green leafy vegetables, meat, nuts/nut oils, poultry, vegetable oils and whole grains. Vitamin E supplements are available in natural or synthetic forms. While the precise rate of vitamin E absorption is not known with certainty, it is believed to be variable and low. Reported rates of absorption of vitamin E following intake with food have varied from as high as 51%-86% to as low as 21%-29% (1). All forms of vitamin E, including all of the tocopherol and tocotrienol homologues, are absorbed through the intestine in a similar manner.
     The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 30 international units (IUs) vitamin E for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Tocopherols, along with tocotrienols, are organic compounds collectively known as vitamin E. Natural tocopherols exist as a mixture of d-alpha-, d-beta-, d-gamma- and d-delta-isoforms, each having antioxidant activities (2). Tocopherols are present in many foods, such as vegetable oils, nuts and grains. They are considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods (21CFR182.3890) (3).

This ingredient can be found in the following products:
   •  PhytoBurst® nutritional chews
   •  PhytoMatrix® caplets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. Yoshida Y, Saito Y, Jones LS, Shigeri Y. Chemical reactivities and physical effects in comparison between tocopherols and tocotrienols: physiological significance and prospects as antioxidants. J Biosci Bioeng. 2007;104:439-45.

3. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

Last updated March, 2009

Print This Ingredient
OpenVitamin E (as mixed tocopherols)

Vitamin E (as mixed tocopherols)

Vitamin E is a fat-soluble vitamin with antioxidant properties. Natural vitamin E exists in eight different forms: alpha, beta, gamma, and delta tocopherol; and alpha, beta, gamma, and delta tocotrienol. Alpha-tocopherol is the most active form in humans. In foods, vitamin E exists primarily as mixed tocopherols. Foods that contain vitamin E include: eggs, fortified cereals, fruit, green leafy vegetables, meat, nuts/nut oils, poultry, vegetable oils and whole grains. Vitamin E supplements are available in natural or synthetic forms. While the precise rate of vitamin E absorption is not known with certainty, it is believed to be variable and low. Reported rates of absorption of vitamin E following intake with food have varied from as high as 51%-86% to as low as 21%-29% (1). All forms of vitamin E, including all of the tocopherol and tocotrienol homologues, are absorbed through the intestine in a similar manner.
     The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 30 international units (IUs) vitamin E for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
     Tocopherols, along with tocotrienols, are organic compounds collectively known as vitamin E. Natural tocopherols exist as a mixture of d-alpha-, d-beta-, d-gamma- and d-delta-isoforms, each having antioxidant activities (2). Tocopherols are present in many foods, such as vegetable oils, nuts and grains. They are considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods (21CFR182.3890) (3).

This ingredient can be found in the following products:
   •  Optimal Support Packets
 

References

References

1. Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press, 2000.

2. Yoshida Y, Saito Y, Jones LS, Shigeri Y. Chemical reactivities and physical effects in comparison between tocopherols and tocotrienols: physiological significance and prospects as antioxidants. J Biosci Bioeng. 2007;104:439-45.

3. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

Last updated March, 2009

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* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.