Mannatech Science

To date, more than 52 patents have been issued worldwide for the technology relating to Mannatech’s Ambrotose® formulations.

Ambrotose® Complex Powder
Immune, cognitive and gastrointestinal health glyconutritional supplement.* Naturally gluten-free.

Ambrotose® Products: Technical Information for You and Your Doctor

About Mannatech’s Glyconutrient Sugars and Healthy Blood Glucose Levels

Ambrotose® Complex Powder: Human Clinical Studies


    

Ingredients

OpenAloe vera extract (inner leaf gel powder)

Aloe vera extract (inner leaf gel powder)

 Aloe vera extract inner leaf gel powder includes Manapol®, a polysaccharide found in aloe vera gel. A unique ingredient exclusive to Mannatech, Incorporated, Manapol is extracted from fresh, washed and filtered gel by a specialized extraction method that yields insoluble fibers and stabilized, high molecular weight (MW) soluble fibers rich in long-chain mannose sugars—beta-(1-4)-acetylated polymannans. Many attribute the benefits of topically and orally-applied aloe vera gel to its polymannan content. The MW of over 20% of Manapol is >800,000. It also contains the monosaccharide sugars glucuronic acid, glucose, galacturonic acid, xylose, galactose, glucosamine, fucose, rhamnose and arabinose, and small amounts of protein, calcium, potassium and sulfate (1),(2),(3).

This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Advanced Ambrotose® powder
   •  Ambrotose®complex powder
   •  NutriVerus™ powder

References

References

1. Luta G, McAnalley B. Aloe vera: chemical composition and methods used to determine its presence in commercial products. GlycoScience & Nutrition 2005;6:1-12.

2. Duncan, C., Ramberg, J., and Sinnott, R. Striking differences in Aloe vera gel carbohydrate composition, molecular weight and particle size distributions following processing will not be addressed by dietary supplement GMPs. Poster Presentation at the 5th Annual Natural Supplements Conference, January 17-20, 2008, Scripps Center for Integrative Medicine, San Diego, California.

3.  Luta G, Duncan C, Sinnott R. Chemical characterization of polysaccharide-rich ingredients from Aloe vera, Larix laricina and Larix occidentalis, and Undaria pinnatifida. Presented at the 6th Annual Natural Supplements Conference, January 22-25, 2009, Scripps Center for Integrative Medicine, San Diego, California.

Last updated April, 2013

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OpenArabinogalactan (from Larix spp. wood)

Arabinogalactan (from Larix spp. wood)

Arabinogalactans are a class of long, densely branched high-molecular weight polysaccharides extracted for commercial uses from the bark of the Eastern and Western Larch trees, Larix larcinia and Larix occidentalis. Their monosaccharide constituents include galactose, arabinose, glucose and mannose (1). Larch arabinogalactans are considered a good source of soluble dietary fiber. Arabinogalactans are common in many food plants, including corn, carrots, tomatoes, pears, wheat and red wine (2)

The amount of arabinogalactan absorbed through the intestine after an oral dose is unclear. Non-absorbed arabinogalactan is fermented by bacteria in the gastrointestinal tract (3),(4). Larch arabinogalactans are approved by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS) (21CFR172.610).

This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Advanced Ambrotose® powder
   •  AmbroStart® drink mix
   •  Ambrotose® Complex capsules
   •  Ambrotose® Complex powder
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  EM•PACT®
   •  Manna-C™ capsules
   •  MannaCLEANSE™ caplets
   •  NutriVerus™ powder
   •  Optimal Support Packets
   •  Phyt-Aloe® capsules or powder
   •  PLUS™ caplets
   •  SPORT™ capsules
 

References

References

 

     1.    Luta G, Duncan C, Sinnott R. Chemical characterization of polysaccharide-rich ingredients from Aloe vera, Larix laricina and Larix occidentalis, and Undaria pinnatifida. Presented at the Scripps Center for Integrative Medicine's 6th Annual Natural Supplements Conference, San Diego, California.January 22-25, 2009. 2009.
     2.    Cui SW. Polysaccharide Gums from Agricultural Products: Processing, Structures & Functionality. Lancaster, Pa.: Technomic Publishing Co., Inc., 2001.
     3.    Crociani F, Alessandrini A, Mucci MM, Biavati B. Degradation of complex carbohydrates by Bifidobacterium spp. Int J Food Microbiol 1994;24:199-210.
     4.    Kelly GS. 'Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide. Altern.Med Rev 1999;4:96-103.

Last updated March, 2013

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OpenGhatti gum

Ghatti gum

 

Ghatti gum, a mixture of complex polysaccharides, comes from the bark of Anogeissus latifolia, a large tree native to India and Sri Lanka. Monosaccharide constituents include arabinose, galactose, mannose, xylose and glucuronic acid. Ghatti gum is used in supplements, foods, drugs and cosmetics. It contains as much as 80% soluble dietary fiber (1).
 
Most gums are believed to be largely degraded in the colon (2). Test tube studies have demonstrated the fermentation of ghatti gum by the beneficial human bacteria species Bifidobacterium (3),(4). Ghatti gum is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is permitted for use as a food (21CFR184.1333).

 This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Advanced Ambrotose® powder
   •  AmbroStart® drink mix
   •  Ambrotose AO® capsules
   •  Ambrotose® Complex capsules
   •  Ambrotose® Complex powder
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  EM•PACT® sports drink
   •  Emprizone® gel
   •  FIRM with Ambrotose® cream
   •  Manna-C™ capsules
   •  MannaCLEANSE™ caplets
   •  Optimal Support Packets
   •  Phyt-Aloe® capsules or powder
   •  PLUS™ caplets
   •  SPORT™ capsules
 

References

References

1. Glicksman M. Gum Ghatti (Indian gum). In: Glicksman M, ed. Food Hydrocolloids. Boca Raton: CRC Press 1983:31-7.

2. Hill MJ. Bacterial fermentation of complex carbohydrate in the human colon. Eur J Cancer Prev 1995;4:353-8.

3. Crociani F, Alessandrini A, Mucci MM, Biavati B. Degradation of complex carbohydrates by Bifidobacterium spp. Int J Food Microbiol 1994;24:199-210.

4. Salyers AA, West SE, Vercellotti JR, Wilkins TD. Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon. Appl Environ Microbiol 1977;34:529-33.

Last updated November 2013

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OpenGlucosamine HCl

Glucosamine HCl

Glucosamine HCl is a salt of the amino monosaccharide, glucosamine, which is used to adjust the pH (the acidity or alkalinity) of cosmetics and personal care products (1).

This ingredient can be found in the following products:
   •  Ambrotose® Complex powder
   •  Mannatech LIFT™ Night Repair Crème
 

References

References

1. International Cosmetic Ingredient Dictionary and Handbook. Washington, D.C.: The Cosmetic, Toiletry and Fragrance Association, 2006.

Last updated November 2013

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OpenGum tragacanth

Gum tragacanth

Gum tragacanth comes from the stems and branches of the flowering plant Astragalus gummifer. The raw gum is made up of a mixture of two polysaccharides. Monosaccharide constituents include galactose, arabinose, xylose, fucose, rhamnose, and galacturonic acid (1). Gum tragacanth has been approved for use in pharmaceuticals in the U.S. since 1820 and in foods since 1925 (2). Most gums are believed to be largely degraded in the colon (3). Test tube studies have demonstrated that gum tragacanth can be digested by a number of bacteria that inhabit the human colon, including the beneficial Bifidobacteria species (4),(5). Gum tragacanth is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is commonly added to foods (21CFR184.1351).

This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Advanced Ambrotose® powder
   •  AmbroStart® drink mix
   •  Ambrotose AO® capsules
   •  Ambrotose® Complex capsules
   •  Ambrotose® Complex powder
   •  CardioBALANCE® capsules
   •  Catalyst™ caplets
   •  EM•PACT® sports drink
   •  Emprizone® gel
   •  FIRM with Ambrotose® cream
   •  Manna-C™ capsules
   •  MannaCLEANSE™ caplets
   •  NutriVerus™ powder
   •  Optimal Support Packets
   •  Phyt-Aloe® capsules or powder
   •  PLUS™ caplets
   •  SPORT™ capsules
 

References

References

1. Anderson DM, Howlett JF, McNab CG. The amino acid composition of the proteinaceous component of gum tragacanth (Asiatic Astragalus spp.). Food Addit Contam 1985;2:231-5.

2.  Anderson DM. Evidence for the safety of gum tragacanth (Asiatic Astragalus spp.) and modern criteria for the evaluation of food additives. Food Addit Contam 1989;6:1-12.

3.  Hill MJ. Bacterial fermentation of complex carbohydrate in the human colon. Eur J Cancer Prev 1995;4:353-8.

4.  Crociani F, Alessandrini A, Mucci MM, Biavati B. Degradation of complex carbohydrates by Bifidobacterium spp. Int J Food Microbiol 1994;24:199-210.

5.  Salyers AA, West SE, Vercellotti JR, Wilkins TD. Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon. Appl Environ Microbiol 1977;34:529-33.

Last updated November 2013

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OpenRice starch

Rice starch

Rice starch is a polysaccharide obtained from rice, Oryza sativa.  Worldwide, natural starch is an important source of energy. Humans and other animals have enzymes that are able to digest starch into its glucose components, so it can be easily digested. Rice starch is an approved food additive by the U.S. Food and Drug Administration (FDA) (1).

This ingredient can be found in the following products:
   •  Advanced Ambrotose® capsules
   •  Advanced Ambrotose® powder
   •  Ambrotose® Complex powder
 

References

References

1. Food and Drug Administration. EAFUS: A Food Additive Database. http://www.foodsafety.gov/~dms/eafus.html. 10-17-2008. 12-4-2008.

Last updated March, 2009

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About Ingredients

Learn more about:

 
    NSF- Certified according to the NSF/ANSI 173 Dietary Supplement Standard—the only American National Standard for dietary supplements. This certification ensures that this product contains only the ingredients indicated on the label and is free of impurities, and that Good Manufacturing Practices (GMPs) were used in the manufacturing facility.
Read more about NSF

 

* This statement has not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.

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