Hypromellose, also known as hydroxypropyl methylcellulose (HPMC), is a derivative of cellulose. In oral products, hypromellose is primarily used as a binder and for encapsulation as an alternative to animal-derived gelatin. In foods, it is used as a thickener and to stabilize oil-in-water mixtures 1. Hypromellose is an approved food additive by the U.S. Food and Drug Administration (FDA) 2.

This ingredient can be found in the following products in United States:


  1. Handbook of Pharmaceutical Excipients. Washington, DC: Pharmaceutical Press and American Pharmacists Assn, 2006.
  2. Food and Drug Administration. EAFUS: A Food Additive Database. 10-17-2008. 12-4-2008.