In a six-month, open-label human studyof 15 retired football players, intake of Mannatech products resulted in statistically significant improvements in numerous self-reported measures of physical and mental health, quality of life, memory, and elbow and knee pain reduction. Study participants took Mannatech’s Ambrotose® complex powder, Omega–3 with Vitamin D3 capsules, Ambrotose AO® capsules, PhytoMatrix® caplets and PLUS™ caplets. All of these products are gluten-free and NSF-certified. Authors include Mannatech scientists Drs. Robert A. Sinnott and Rolando L. Maddela, Dr. Sejong Bae of the University of North Texas Health Science Center and Dr. Talitha Best of the University of South Australia, Adelaide.