Alpha-galactosidase is an enzyme that hydrolyzes the terminal galactose monosaccharide from oligosaccharides, glycolipids and glycoproteins. Plant-derived oligo- and polysaccharides consumed in high-fiber diets normally pass through the small intestine intact to be fermented by colonic bacteria, a process that produces gas that can lead to flatulence. Alpha-galactosidase, derived from the fungus Aspergillus niger, has been consumed as a digestive aid for over 15 years 1. It is approved for use as a food additive by the U.S. Food and Drug Administration (FDA) 2.

This ingredient can be found in the following products in United States:


  1. Alpha-galactosidase to prevent gas. Med Lett Drugs Ther 1993;35:29-30.
  2. Food and Drug Administration. EAFUS: A Food Additive Database. 10-17-2008. 12-4-2008.