Bromelain, extracted from the stem and fruit of the pineapple plant (Ananas comosus), is an enzyme that digests proteins. It was introduced as a dietary supplement in 1957 and has been used in many clinical trials since then. Bromelain is approved by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS) (21CFR184.1024).

This ingredient can be found in the following products in United States: