Caffeine belongs to a group of compounds known as methylxanthines. Naturally occurring in more than 60 plants, including coffee (Coffea arabica) beans, cocoa (Theobroma cacao) beans, guarana (Paullinia cupana) berries and tea (Camellia sinensis) leaves, caffeine is the most popular psychoactive chemical in the world 1.
After oral intake, 99% of caffeine is absorbed and then widely distributed throughout the tissues of the body. It does not accumulate and it is extensively metabolized in the liver. Caffeine and its metabolites are excreted in the urine. Its plasma half-life is variable, ranging roughly 3-10 hours. Caffeine stimulates the central nervous system, heart rate, and respiration, has mood-altering properties and functions as a mild diuretic 1.
In human clinical studies, intake of caffeine has been shown to improve cognitive performance 2 ,3 and alertness 4 ,5. Caffeine may also support healthy weight management, as it increases energy expenditure6 and thermogenesis7.
Caffeinated products are not intended or recommended for children and those sensitive to caffeine. Pregnant or nursing women, those with a medical condition, and those taking medication should consult a healthcare professional before use of caffeinated products.