Chromium is an essential trace element that plays an important role in normal blood sugar regulation. Sources of dietary chromium include high-bran cereals, meats, poultry, fish and some beers and red wines. No adverse effects have been associated with chromium intake from food or supplements 1.
The U.S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 120 μg chromium for adults and children 4 or more years of age (21CFR101.9). RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels.
In a 16-week randomized, double-blind, placebo-controlled trial of 60 adults, subjects who consumed milk containing 200 mcg chromium from chromium chloride experienced no adverse events, other than mild complaints of constipation (5% of subjects) and flatulence (5% of subjects) 2.