Chromium polynicotinate

Chromium is an essential trace element that plays an important role in normal blood sugar regulation 1, 2. Sources of dietary chromium include high-bran cereals, meats, poultry, fish and some beers and red wines 1, 2, 3. Only small amounts (<2.5%) of dietary chromium are absorbed through the intestine 1. Chromium, in the trivalent form (CR III) is generally well tolerated 2. The U. S. Food and Drug Administration (FDA) has established a Reference Daily Intake (RDI) of 35 µ (or mcg) chromium for adults and children 4 or more years of age (21CFR101.9)(previously the DV, or Daily Value for chromium was 120 mcg for adults and children 4 years or older) 3, 4. RDIs are a set of dietary references for essential vitamins and minerals that are considered amounts sufficient to meet the daily requirements of healthy individuals. RDIs serve as the basis for calculating the percent daily value (%DV) amounts found on dietary supplement and food labels 3, 4.

Chromium polynicotinate, because it induces chromium bound to molecules of niacin, is often called niacin bound chromium 2, 5. Chromium polynicotinate is a chromium salt used in supplements 2.

This ingredient can be found in the following products in United States:


  1. Institute of Medicine (IOM). 2001. Dietary Reference Intakes (DRIs) for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: The National Academies Press (US).
  2. Natural Medicines databases – Professional. Chromium. Product ID No. 932. Subscription required. Reviewed 1/3/2019. Updated 4/10/2019. Accessed 6/3/2019.,-herbs-supplements/professional.aspx?productid=932
  3. Chromium. Dietary Supplement Fact Sheet. National Institutes of Health (NIH). Office of Dietary Supplements (ODS). Updated 9/21/2018. Accessed 6/3/2019.
  4. U. S. Food and Drug Administration (FDA). Electronic Code of Federal Regulations (e-CFR) 21e-CFR101.9 Nutrition labeling of food. Current as of 5/30/2019. Accessed 6/3/2019.
  5. Lydic ML, McNurlan M, Bembo S., et al. Chromium picolinate improves insulin sensitivity in obese subjects with polycystic ovary syndrome. Fertil Steril 2006; 86: 243-246.