D-alpha-tocopheryl acetate

D-alpha-tocopheryl acetate, or D-alpha tocopherol acetate, is an organic compound derived from vegetable oils that acts as a source of vitamin E. The natural form, d-alpha-tocopheryl acetate, is more bioavailable than the synthetic form, dl-alpha-tocopheryl acetate. Alpha-tocopheryl acetate is converted to alpha-tocopherol in the intestine before being absorbed 1. Alpha-tocopherol, like other forms of vitamin E, demonstrates antioxidant activity 2. Alpha-tocopherol acetate is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in foods 3.


  1. Acuff RV, Thedford SS, Hidiroglou NN, Papas AM, Odom TA, Jr. Relative bioavailability of RRR- and all-rac-alpha-tocopheryl acetate in humans: studies using deuterated compounds. Am J Clin Nutr 1994;60:397-402.