Grape skin extract

Grape skin extract. Grapes, the fruit of the grape vine Vitis vinifera, are the leading fruit crop in the world. Although they are popular as a fresh fruit, grapes are also used to make juices, jams, jelly, raisins and wine 1. Many health benefits provided by grapes and their products are attributed to their abundant polyphenols. The polyphenols in grapes include resveratrol and flavonoids: quercetin (and its glycoside, rutin), kaempferol, anthocyanins, tannins and myricetin. These compounds are present in the skins, seeds and stems of the grape and many demonstrate potent antioxidant activity 2. Grapes also contain plant acids, sugars, amino acids, minerals and small amounts of vitamins C and E 3, 4. Grape skin extract is considered generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use in the coloring of beverages and other foods (21CFR73.170) 5.

This ingredient can be found in the following products in United States:


  1. Ensminger AH, Ensminger ME, Konlande JE, Robson JRK. The Concise Encyclopedia of Foods and Nutrition. Boca Raton, Florida: CRC Press, 1995.
  2. Torres JL, Varela B, Garcia MT et al. Valorization of grape (Vitis vinifera) byproducts. Antioxidant and biological properties of polyphenolic fractions differing in procyanidin composition and flavonol content. J Agric Food Chem 2002;50:7548-55.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics. New York: John Wiley & Sons, Inc., 1996.
  4. Soleas GJ, Diamandis EP, Goldberg DM. J Clin Lab Anal. 1997;11:287-313.
  5. Food and Drug Administration. EAFUS: A Food Additive Database. 10-17-2008. 12-4-2008.