Manapol® Glyco Nutrient Blend (Proprietary)

Aloe vera inner leaf gel powder (Manapol®) is the powder obtained from the ethanol precipitated, freeze-dried gel from the leaves of the aloe vera plant, Aloe barbadensis.

For centuries, the plant aloe vera has been used by cultures for its beneficial effects on human health 1.* Today aloe vera gel continues to be used in supplements, foods, beverages, and cosmetics. Aloe leaves consist of two major parts, the outer leaf epidermis and the inner leaf gel, which are very different in their chemical composition and properties. Aloe gel is obtained from the inner portion of the leaves. Aloe gel is rich in nutrients and contains an abundant supply of glycoproteins and mono-, oligo- and polysaccharides. Monosaccharide constituents include glucose, mannose, galacturonic acid, glucuronic acid, galactose, arabinose, fucose, glucosamine, fructose, rhamnose and xylose 2.

Much of the health benefits observed by the use of aloe vera gel may be attributed to its high molecular weight polysaccharides.* Before a process was developed to stabilize aloe vera gel or extracts, fresh preparations were regarded as being required for any therapeutic efficacy 3.* It has now been shown that careful drying of aloe vera gel can retain the polysaccharide content important for producing many of its health benefits 4.*


  1. The Merck Index. Whitehouse Station, NJ: Merck & Co., Inc., 1996.
  2. Duncan, C., Ramberg, J., and Sinnott, R. Striking differences in Aloe vera gel carbohydrate composition, molecular weight and particle size distributions following processing will not be addressed by dietary supplement GMPs. Poster Presentation at the 5th Annual Natural Supplements Conference, January 17-20, 2008, Scripps Center for Integrative Medicine, San Diego, California.
  3. Gjerstad G, Riner TD. Current status of aloe as a cure-all. Am J Pharm Sci Support Public Health 1968;140:58-64.
  4. Ni Y, Turner D, Yates KM, Tizard I. Isolation and characterization of structural components of Aloe vera L. leaf pulp. Int J Immunopharmacol. 2004;4:1745-55.