Protease (from Aspergillus melleus, Aspergillus oryzae)

Proteases are protein-digesting enzymes. While they occur naturally in all organisms, proteases in supplements are typically obtained from safe, non-pathogenic fungi, such as Aspergillus melleus and Aspergillus oryzae. Orally administered protein-digesting enzymes can be detected in human blood, at least to some extent, in their intact, biologically active form 1.


  1. Kolac C, Streichhan P, Lehr C-M. Oral bioavailability of proteolytic enzymes. Eur J Pharmacol Biopharm 1996;42:222-32.