Proteases are protein-digesting enzymes. While they occur naturally in all organisms, proteases in supplements are typically obtained from safe, non-pathogenic fungi. Orally administered protein-digesting enzymes can be detected in human blood, at least to some extent, in their intact, biologically active form 1.

This ingredient can be found in the following products in United States:


  1. Kolac C, Streichhan P, Lehr C-M. Oral bioavailability of proteolytic enzymes. Eur J Pharmacol Biopharm 1996;42:222-32.