Pyridoxal 5′-phosphate

Pyridoxal 5’-phosphate (P5P) is the active coenzyme form of vitamin B6, involved in amino acid metabolism and numerous other enzymatic reactions in the human body. Pyridoxal 5’-phosphate is considered a particularly useful nutrient supplement, because all other forms of vitamin B6 must be converted to P5P in the liver before they are considered active. The P5P form of vitamin B6 is typically found in foods of animal origin, such as meats, dairy products and eggs. No adverse effects have been associated with high intake of vitamin B6 from food sources 1.


  1. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press, 2000.