In a five-week combined Phase 1 and 2 open label, forced titration dose response study of 21 healthy adults, physicians and scientists from Australia and New Zealand showed that four capsules/day of the Ambrotose AO® dietary supplement appear to be safe and raised serum oxygen radical absorption capacity (ORAC) by 36.6%.* Study was at least partially funded by Mannatech.


Myers SP, Stevenson L, Cheras PA, et al. (2010) A forced titration study of the antioxidant and immunomodulatory effects of Ambrotose AO supplement. BMC Comp Alt Med 10, doi: 10.1186/1472-6882-10-16.

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