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  • University of Ghent Scientists Publish Ambrotose® Product Prebiotic Study

    University of Ghent
    University of Ghent

    A study that employed state-of-the-art technology to further explore the prebiotic effects of Ambrotose products has been published in the Antonie van Leeuwekhoek Journal of Microbiology (1). The study was conducted by scientists at ProDigest in collaboration with the Laboratory of Microbial Ecology and Technology (LabMET) at Ghent University, in Belgium.

    As The Economist magazine’s recent cover story, “Microbes Maketh Man”, made clear, the bacteria that populate the human body—particularly those in the gut—have an enormous impact on our health. LabMET scientists are leaders in the development of tools to better assess human gut bacterial populations.This is the first study to apply 16sRNA genes-based pyrosequencing in a Simulator of the Human Intestinal Microbial Ecosystem (SHIME) study. The pyrosequencing technique allowed Belgian scientists to explore more deeply findings from a previous study published by Ghent University scientists, showing that Advanced Ambrotose powder exhibited prebiotic effects along the entire colon (2).

    Scientists at ProDigest are devoted to investigating the optimal management of microbial resources, with the goal of developing novel products and processes that can improve the environment or human health in the most sustainable way.Study was at least partially funded by Mannatech.

    Link to Abstract

    1. Marzorati M, Maignien L, Verhelst A et al. Barcoded pyrosequencing analysis of the microbial community in a simulator of the human gastrointestinal tract showed a colon region-specific microbiota modulation for two plant-derived polysaccharide blends. Antonie Van Leeuwenhoek. Published online October 5, 2012.
    2. Marzorati M, Verhelst A, Luta G et al. In vitro modulation of the human gastrointestinal microbial community by plant-derived polysaccharide-rich dietary supplements. Int J Food Microbiol 2010;139:168-76.
    Oct 11, 2012 at 4:00 pm | Publications